Generally shorter duration than primary with decreasing frequency and severity over time. Generally lasts 2-4 weeks if untreated before spontaneous resolve. Prodromal symptoms of itching, burning, and paresthesias common prior to development and skin and mucosal lesions. Generally less symptomatic with lesions occurring in the same distribution due to reactivation of latent infection in the affected nerve roots. Generally more painful and symptomatic with tender regional lymphadenopathy, fever, headache and malaise +/- other systemic symptoms. Often secondary to variety of stressors including acute illness/injury, immunosuppression, physiologic stress, and menses.Ĭluster of erythematous, painful lesions, which quickly ulcerate (external genitalia, perineum, buttocks, rectum, and oropharynx).ĭysuria is common secondary to proximity of lesions to the urethra. Infection with HSV-1 or HSV-2 in absence of pre-existing antibodies. Question 3) Differentiate between primary and recurrent herpes infection Genital Herpes Infection
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